CHEMBL157206


SMILES C=CCc1cccc(CC=C)c1OC(C)C1=NCCN1
InChIKey YAYASQTZIRSRFB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 270.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.56 6.56 6.56 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.89 6.89 6.89 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.78 7.78 7.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 6.3 6.3 6.3 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 7.25 7.25 7.25 ChEMBL