CHEMBL167223


SMILES CC(C1=C(CCN(C)C)Cc2cc(Cl)ccc21)c1ccccn1
InChIKey RPUXCIYWJSVFFV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 326.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.14 6.14 6.14 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.48 6.48 6.48 ChEMBL
H1 HRH1 Human Histamine A pKi 9.09 9.09 9.09 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.02 7.02 7.02 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.82 6.82 6.82 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.48 7.48 7.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database