BAY1214784


SMILES ClC1=C(CNC(C2=CC=C3N(S(=O)(C4=CC=C(F)C=C4)=O)[C@@H](C5CC5)C6(CCS(CC6)(=O)=O)C3=C2)=O)N=CC(C(F)(F)F)=C1
InChIKey PZGSYNNVPNLHQG-SANMLTNESA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 671.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pKd 8.01 8.13 8.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pIC50 7.68 7.68 7.68 Guide to Pharmacology
CB1 CNR1 Human Cannabinoid A pIC50 5.46 5.46 5.47 ChEMBL
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pIC50 7.57 7.62 7.68 ChEMBL