CHEMBL157955


SMILES CCc1cccc(CC)c1OC(C)C1=NCCN1
InChIKey OXGCVSXSSWZTMU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 246.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.57 6.57 6.57 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.56 6.56 6.56 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.5 7.5 7.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 6.0 6.0 6.0 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 7.56 7.56 7.56 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 7.93 7.93 7.93 ChEMBL