CHEMBL168611
SMILES | CCC[C@H]1CN(Cc2ccccc2)C[C@H]1CNC(=O)c1cc(Cl)c(NC)cc1OC |
InChIKey | FPHFICIJDHPAHE-RBUKOAKNSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 2 |
Rotatable bonds | 9 |
Molecular weight (Da) | 429.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D2 | DRD2 | Human | Dopamine | A | pKi | 7.35 | 7.45 | 7.55 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.51 | 6.51 | 6.51 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 7.34 | 7.34 | 7.34 | ChEMBL |
D1 | DRD1 | Bovine | Dopamine | A | pKi | 6.62 | 6.62 | 6.62 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |