CHEMBL169889
SMILES | COc1ccc(Br)cc1C1=NCC[C@H](CN2CCN(c3ccccc3)CC2)N1 |
InChIKey | RVBVZFLMCDGFOZ-GOSISDBHSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 1 |
Rotatable bonds | 5 |
Molecular weight (Da) | 442.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D3 | DRD3 | Human | Dopamine | A | pKi | 5.13 | 5.13 | 5.13 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 4.36 | 4.37 | 4.37 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 5.8 | 5.8 | 5.8 | ChEMBL |
D1 | DRD1 | Bovine | Dopamine | A | pKi | 4.82 | 4.82 | 4.82 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |