(S,R)-MEFLOQUINE


SMILES O[C@@H](c1cc(C(F)(F)F)nc2c(C(F)(F)F)cccc12)[C@H]1CCCCN1
InChIKey XEEQGYMUWCZPDN-DOMZBBRYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 378.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A1 AA1R Human Adenosine A pKi 8.23 8.23 8.23 Drug Central
A2A AA2AR Human Adenosine A pKi 5.18 5.18 5.18 ChEMBL
A1 AA1R Human Adenosine A pKi 4.85 4.85 4.85 ChEMBL
A2A AA2AR Human Adenosine A pKi 8.16 8.16 8.16 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database