CHEMBL176169


SMILES Cc1ccc2n1C=C(N1CCN(C)CC1)c1ccccc1S2
InChIKey RLPMXJWKLTTXDD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 311.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKi 8.57 8.57 8.57 ChEMBL
D3 DRD3 Rat Dopamine A pKi 7.75 7.75 7.75 ChEMBL
D1 DRD1 Rat Dopamine A pKi 7.15 7.15 7.15 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 5.64 5.64 5.64 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.9 6.9 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database