CHEMBL160626


SMILES N#Cc1cccc2c(CN3CCN(c4ccc(Cl)cc4)CC3)cnn12
InChIKey STIRDGXSGQTCAJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 351.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.6 5.6 5.6 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.82 8.82 8.82 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.58 4.58 4.58 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.66 5.66 5.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.35 4.36 4.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.82 8.82 8.82 ChEMBL