CHEMBL16123


SMILES Cn1c(=O)sc2cc(CCCCN3CCC(Cc4ccccc4)CC3)ccc21
InChIKey ZBVBPDNSLDPENM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 394.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKi 8.05 8.05 8.05 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 6.7 6.7 6.7 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.0 7.0 7.0 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.52 7.52 7.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database