CHEMBL1627304


SMILES COc1ccccc1N1CCN(C/C=C/CNC(=O)c2cc3ccccc3s2)CC1
InChIKey CECKJAHVLJLQBE-VOTSOKGWSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 421.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.17 6.17 6.17 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.58 8.58 8.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 8.96 8.96 8.96 ChEMBL