CHEMBL1630940


SMILES COc1ccc(C[C@@H](C)NCCOc2ccccc2OCC(F)(F)F)cc1S(N)(=O)=O
InChIKey CPWQIBJELMVKCH-CQSZACIVSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 462.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 9.02 9.02 9.02 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 8.96 8.96 8.96 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 8.26 8.26 8.26 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 9.58 9.58 9.58 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.02 9.02 9.02 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 9.22 9.22 9.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database