CLOBENPROBIT


SMILES N=C(NCc1ccc(Cl)cc1)SCCCCc1c[nH]cn1
InChIKey PLYSQHFCSVNUMZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 322.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 8.1 8.1 8.1 ChEMBL
H3 HRH3 Human Histamine A pKi 8.6 8.6 8.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 7.7 7.7 7.7 ChEMBL
H3 HRH3 Human Histamine A pEC50 9.4 9.4 9.4 ChEMBL