CHEMBL1632412


SMILES Cc1ccc2[nH]c(/C(=N\O)C3CCN(C)CC3)cc2c1
InChIKey VOIJIMTXMUBFDD-VLGSPTGOSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 271.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pKi 7.7 7.7 7.7 ChEMBL
H4 HRH4 Rat Histamine A pKi 6.7 6.7 6.7 ChEMBL
H4 HRH4 Human Histamine A pKi 7.3 7.3 7.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Mouse Histamine A pEC50 6.7 6.7 6.7 ChEMBL
H4 HRH4 Rat Histamine A pEC50 6.3 6.3 6.3 ChEMBL
H4 HRH4 Human Histamine A pEC50 7.0 7.0 7.0 ChEMBL