CHEMBL1632413
| SMILES | CN1CCN(/C(=N\O)c2cc3cc(Cl)ccc3[nH]2)CC1 |
| InChIKey | YSEFYTJOKARSSH-VKAVYKQESA-N |
Chemical properties
| Hydrogen bond acceptors | 3 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 1 |
| Molecular weight (Da) | 292.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| H4 | HRH4 | Mouse | Histamine | A | pKi | 8.1 | 8.1 | 8.1 | ChEMBL |
| H4 | HRH4 | Rat | Histamine | A | pKi | 7.7 | 7.7 | 7.7 | ChEMBL |
| H4 | HRH4 | Human | Histamine | A | pKi | 7.5 | 7.5 | 7.5 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| H4 | HRH4 | Mouse | Histamine | A | pEC50 | 8.0 | 8.0 | 8.0 | ChEMBL |
| H4 | HRH4 | Rat | Histamine | A | pEC50 | 8.0 | 8.0 | 8.0 | ChEMBL |
| H4 | HRH4 | Human | Histamine | A | pEC50 | 7.4 | 7.4 | 7.4 | ChEMBL |