CHEMBL168372


SMILES COc1cc(N(C)C(C)=O)c(Cl)cc1C(=O)NC[C@@H]1CCN(Cc2ccccc2)C1
InChIKey PCPQHGBAGOWPLH-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 429.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.12 4.12 4.12 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.38 5.38 5.38 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.14 5.14 5.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.52 4.62 4.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database