CHEMBL1684028


SMILES CCCN1CCc2cccc3c2C1Cc1cccc(OCc2cn(CCCCN4CCN(c5ccccc5OC)CC4)nn2)c1-3
InChIKey OXHFCAMGABAVGJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 12
Molecular weight (Da) 606.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 5.57 5.57 5.57 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.57 8.57 8.57 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.76 6.76 6.76 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.01 8.01 8.01 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.18 6.18 6.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database