CHEMBL1834410


SMILES CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)CC(C)(C)C)[C@H]1Cc4ccc(O)c5c4[C@@]3(CCN1CC1CC1)[C@H]2O5
InChIKey RIMTXZIUOVDSSA-JLXZXSBASA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 481.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.73 7.73 7.73 ChEMBL
δ OPRD Human Opioid A pKi 8.9 8.9 8.9 ChEMBL
κ OPRK Human Opioid A pKi 8.8 8.8 8.8 ChEMBL
μ OPRM Human Opioid A pKi 8.53 8.53 8.53 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.3 7.3 7.3 ChEMBL
μ OPRM Human Opioid A pEC50 8.59 8.59 8.59 ChEMBL