CHEMBL184383
SMILES | O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cc2cc(I)ccc2o1 |
InChIKey | OBGOWZOSTXHAGD-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 1 |
Rotatable bonds | 7 |
Molecular weight (Da) | 571.0 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D1 | DRD1 | Pig | Dopamine | A | pKi | 5.48 | 5.48 | 5.48 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 5.66 | 5.71 | 5.76 | ChEMBL |
D1 | DRD1 | Human | Dopamine | A | pKi | 5.54 | 5.54 | 5.54 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 8.24 | 8.52 | 8.8 | ChEMBL |
5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 6.89 | 6.89 | 6.89 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 5.5 | 5.94 | 6.37 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D3 | DRD3 | Human | Dopamine | A | pIC50 | 6.28 | 6.28 | 6.28 | ChEMBL |