CHEMBL185455


SMILES C[C@H]1CN(/C(=N/c2ccc(C(=O)NCCc3ccc(Cl)cc3Cl)cc2)NC2CCCCC2)CCN1
InChIKey PBZOSRKDAHPMMH-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 515.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pKi 7.68 7.68 7.68 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.55 5.55 5.55 ChEMBL
MC4 MC4R Human Melanocortin A pKi 6.24 6.24 6.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pIC50 6.42 6.42 6.42 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 5.75 5.75 5.75 ChEMBL