CHEMBL186439


SMILES CNC1CCN(/C(=N/c2ccc(C(=O)NCCc3ccc(Cl)cc3Cl)cc2)NC2CCCCC2)C1
InChIKey VMEVITMYQPTNSR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 515.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pKi 7.44 7.44 7.44 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.64 5.64 5.64 ChEMBL
MC4 MC4R Human Melanocortin A pKi 5.85 5.85 5.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pIC50 6.2 6.2 6.2 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 5.34 5.34 5.34 ChEMBL