CHEMBL188622


SMILES CS(=O)(=O)Oc1cccc2c(CCNC[C@H](O)c3cccc(NS(=O)(=O)c4cccs4)c3)c[nH]c12
InChIKey TVOPQHIKUYPQLB-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 4
Rotatable bonds 11
Molecular weight (Da) 535.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKi 6.64 6.64 6.64 ChEMBL
β3 ADRB3 Human Adrenoceptors A pKi 7.48 7.48 7.48 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKi 6.65 6.65 6.65 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β3 ADRB3 Human Adrenoceptors A pEC50 8.77 8.77 8.77 ChEMBL