CHEMBL1765631


SMILES CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)C1CCn2ncc(C=O)c2C1
InChIKey LOJUPRHIDKSORB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 458.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 4.64 4.64 4.64 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.2 5.2 5.2 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.41 7.41 7.41 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.08 5.21 5.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database