CHEMBL1767156


SMILES CN1CCC(n2nc(Cc3ccc(Cl)cc3)c3ccccc3c2=O)CC1
InChIKey FRUMSZUUBXPHHF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 367.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 8.2 8.2 8.2 ChEMBL
H1 HRH1 Human Histamine A pKi 9.0 9.0 9.0 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.8 7.8 7.8 ChEMBL
H3 HRH3 Human Histamine A pKi 6.9 6.9 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database