CHEMBL1916551


SMILES CCCCn1cc(CCCOc2ccc(C(=O)NCCCCN(CCC)C3Cc4ccccc4C3)cc2OC)nn1
InChIKey SHGYUZFUKMSIQE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 18
Molecular weight (Da) 561.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.22 5.22 5.22 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.38 7.38 7.38 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.15 9.15 9.15 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.92 8.16 8.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 7.89 7.89 7.89 ChEMBL