CHEMBL192099


SMILES O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2ccc(F)c(F)c2)CC1
InChIKey RZWIBVNDYKVOQZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 391.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 6.8 6.8 6.8 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 5.85 5.85 5.85 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.1 8.1 8.1 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 5.39 5.39 5.39 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.26 7.26 7.26 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.66 5.66 5.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database