CHEMBL1774101


SMILES COc1ccccc1C1CCN(Cc2nc3ccccc3n2C)CC1
InChIKey MJDLYRJRCRLNGE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 335.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.37 6.37 6.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 7.06 7.06 7.06 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.02 6.02 6.02 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 6.06 6.06 6.06 ChEMBL