CHEMBL1928122


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccc(OCCOCCOCCOCCOc3cccc(C(=O)NCCCCN4CCN(c5ccccc5OC)CC4)c3)c2)CC1
InChIKey LEFBFLOSCAEZAG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 13
Hydrogen bond donors 2
Rotatable bonds 30
Molecular weight (Da) 924.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A Q9TSW7 Pig Adrenoceptors A pKi 9.01 9.01 9.01 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.7 6.7 6.7 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.32 7.32 7.32 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.18 8.46 8.74 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.21 9.21 9.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database