CHEMBL1928137


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cnn3ccc(OCCOCCOCCOCCOc4ccn5ncc(C(=O)NCCCCN6CCN(c7ccccc7OC)CC6)c5c4)cc23)CC1
InChIKey OSAOKFNDHSEFAK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 17
Hydrogen bond donors 2
Rotatable bonds 30
Molecular weight (Da) 1004.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A Q9TSW7 Pig Adrenoceptors A pKi 8.96 8.96 8.96 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.38 6.38 6.38 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.11 7.11 7.11 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.47 9.47 9.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.74 8.98 9.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database