CHEMBL1935571


SMILES CN1CCN(c2nc(N)nc3cc(-c4ccoc4)ccc23)CC1
InChIKey ZULPGIJFVSVHRG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 309.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 8.22 8.31 8.4 ChEMBL
H1 HRH1 Human Histamine A pKi 5.13 5.13 5.13 ChEMBL
H3 HRH3 Human Histamine A pKi 6.73 6.73 6.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pIC50 7.33 7.33 7.33 ChEMBL