CHEMBL193620


SMILES O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2cc(F)c(F)cc2F)CC1
InChIKey AUQZROKGNYIFMG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 409.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.64 7.64 7.64 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.42 6.42 6.42 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.72 8.72 8.72 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 5.36 5.36 5.36 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.44 6.44 6.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.16 6.16 6.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database