CHEMBL193639


SMILES CN(C)C[C@H]1CC2c3ccccc3Sc3ccc(F)cc3[C@H]2O1
InChIKey BSOLCASXROXPRZ-MQSINFNDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 329.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pKi 7.14 7.19 7.23 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.18 8.2 8.21 ChEMBL
H1 HRH1 Human Histamine A pKi 9.22 9.25 9.28 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.1 7.14 7.18 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.28 8.4 8.52 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 9.68 9.68 9.68 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.72 8.34 8.96 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.25 9.43 9.62 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.64 8.71 8.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database