CHEMBL1940408
SMILES | Fc1ccc(CCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1 |
InChIKey | ARWONURFSGKTJW-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 2 |
Hydrogen bond donors | 0 |
Rotatable bonds | 6 |
Molecular weight (Da) | 346.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D4 | DRD4 | Rat | Dopamine | A | pKi | 8.11 | 8.11 | 8.11 | ChEMBL |
D5 | DRD5 | Human | Dopamine | A | pKi | 5.75 | 5.75 | 5.75 | ChEMBL |
D1 | DRD1 | Human | Dopamine | A | pKi | 6.23 | 6.23 | 6.23 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.58 | 6.58 | 6.58 | ChEMBL |
5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pKi | 7.09 | 7.09 | 7.09 | ChEMBL |
5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 6.95 | 6.95 | 6.95 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.55 | 6.55 | 6.55 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |