CHEMBL1940420


SMILES Fc1ccc(OCCCN2CCN(c3ccccn3)CC2)cc1
InChIKey BPDDCCYSOYRMEC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 315.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.74 8.74 8.74 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.08 5.08 5.08 ChEMBL
D5 DRD5 Human Dopamine A pKi 5.62 5.62 5.62 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.71 6.71 6.71 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.68 6.68 6.68 ChEMBL
H1 HRH1 Human Histamine A pKi 6.58 6.58 6.58 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.64 6.64 6.64 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.44 8.44 8.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.73 6.73 6.73 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.75 6.75 6.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database