CHEMBL194206


SMILES COc1ccc(NC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1N1CCN(C)CC1
InChIKey AOENLUNXEDMDRT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 427.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.42 7.42 7.42 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.77 6.77 6.77 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.35 5.35 5.35 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database