N-{4-[4-(3-chloro-2-methoxyphenyl)piperazin-1-yl]butyl}-1-ferra-1,1'-spirobi[pentacyclo[2.2.0.0^{1,3}.0^{1,5}.0^{2,6}]hexane]-2,2',4,4'-tetraene-6-carboxamide
SMILES | None |
InChIKey | None |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D1 | DRD1 | Pig | Dopamine | A | pKi | 5.66 | 5.66 | 5.66 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 9.04 | 9.04 | 9.04 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 8.46 | 8.46 | 8.46 | ChEMBL |
5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 7.85 | 7.85 | 7.85 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 7.0 | 7.07 | 7.14 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D4 | DRD4 | Human | Dopamine | A | pEC50 | 7.64 | 7.65 | 7.66 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pEC50 | 8.01 | 8.01 | 8.01 | ChEMBL |