CHEMBL1813057
SMILES | C[C@@H]1CCCN1CCCOc1ccc(-c2ccc(=O)n(C)n2)cc1 |
InChIKey | LWTPHINMYBPWKW-OAHLLOKOSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 0 |
Rotatable bonds | 6 |
Molecular weight (Da) | 327.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H3 | HRH3 | Rat | Histamine | A | pKi | 8.2 | 8.21 | 8.22 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pKi | 8.85 | 8.89 | 9.0 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
H3 | HRH3 | Rat | Histamine | A | pEC50 | 8.66 | 8.66 | 8.66 | ChEMBL |
H3 | HRH3 | Human | Histamine | A | pEC50 | 9.0 | 9.0 | 9.0 | ChEMBL |