CHEMBL183871


SMILES O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cc2cc(I)ccc2s1
InChIKey PKBFRDZADXJQRC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 587.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.85 5.85 5.85 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.26 6.26 6.26 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.35 8.35 8.35 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.35 6.6 6.85 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.34 7.34 7.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database