CHEMBL184383


SMILES O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cc2cc(I)ccc2o1
InChIKey OBGOWZOSTXHAGD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 571.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.48 5.48 5.48 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.66 5.71 5.76 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.54 5.54 5.54 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.24 8.52 8.8 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.89 6.89 6.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.5 5.94 6.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 6.28 6.28 6.28 ChEMBL