CHEMBL184770


SMILES Cc1cccc(N2CCN(CCc3ccc4[nH]nnc4c3)CC2)c1C
InChIKey IOUSMYRYFCYRJU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 335.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 5.33 5.33 5.33 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.84 7.84 7.84 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.29 8.29 8.29 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.08 7.08 7.08 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.29 7.29 7.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database