CHEMBL184993


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3cc(I)ccc3s2)CC1
InChIKey YIUMSISCOUIOHZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 549.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.28 6.28 6.28 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.38 7.38 7.38 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.07 9.07 9.07 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.57 7.57 7.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.32 8.16 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database