CHEMBL185035


SMILES CC(N[C@H]1CCNC1)c1ccccc1N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@H]2Cc3ccccc3CN2)CC1
InChIKey YUWKIIAXKBDHDF-ULPYORLWSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 9
Molecular weight (Da) 614.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.68 5.68 5.68 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.23 6.23 6.23 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.44 5.44 5.44 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.89 7.89 7.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pEC50 7.92 7.92 7.92 ChEMBL