CHEMBL185836


SMILES C[C@H](Cc1c[nH]c2ccccc12)NC[C@H](O)c1cccc(NS(=O)(=O)c2cccs2)c1
InChIKey MHWIKAADEJCYCU-ZHRRBRCNSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 9
Molecular weight (Da) 455.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β3 ADRB3 Human Adrenoceptors A pKi 7.52 7.52 7.52 ChEMBL
β1 ADRB1 Human Adrenoceptors A pKi 6.96 6.96 6.96 ChEMBL
β2 ADRB2 Human Adrenoceptors A pKi 7.29 7.29 7.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β3 ADRB3 Human Adrenoceptors A pEC50 9.06 9.06 9.06 ChEMBL
β1 ADRB1 Human Adrenoceptors A pEC50 7.18 7.43 7.68 ChEMBL
β2 ADRB2 Human Adrenoceptors A pEC50 7.18 7.43 7.68 ChEMBL