CHEMBL186456


SMILES CN1CCC(C(=O)c2cc3cc(Cl)ccc3[nH]2)CC1
InChIKey FHRAPXRGARHUGJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 276.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.7 6.7 6.7 ChEMBL
H3 HRH3 Human Histamine A pKi 5.5 5.5 5.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pEC50 6.0 6.0 6.0 ChEMBL