CHEMBL2022272


SMILES Clc1ccc2c(c1)N=C(N1CCN(CCc3ccccc3)CC1)c1cccnc1O2
InChIKey KMWUPPLGFWGMEM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 418.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 6.43 6.43 6.43 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.38 7.38 7.38 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database