bumetanide


SMILES CCCCNc1cc(cc(c1Oc1ccccc1)S(=O)(=O)N)C(=O)O
InChIKey MAEIEVLCKWDQJH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 364.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR35 GPR35 Human A orphans A pEC50 8.26 8.26 8.26 Drug Central
NPS NPSR1 Human Neuropeptide S A Potency 5.5 5.5 5.5 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 5.2 5.2 5.2 ChEMBL
GPR35 GPR35 Human A orphans A pEC50 5.0 5.27 5.54 Guide to Pharmacology