CHEMBL202538


SMILES C[C@@H](Cn1ccc2ccc3ncccc3c21)NCc1ccccc1Cl
InChIKey DRERWZQTMBLMNH-HNNXBMFYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 349.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.41 7.41 7.41 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.17 6.17 6.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.36 7.36 7.36 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.13 7.13 7.13 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.2 6.2 6.2 ChEMBL