CHEMBL1086756
SMILES | CCCn1c(-c2ccccc2)cc(C(=O)NCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c1C |
InChIKey | QQGJOZLAJLPARG-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 1 |
Rotatable bonds | 9 |
Molecular weight (Da) | 512.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT7 | 5HT7R | Human | 5-Hydroxytryptamine | A | pIC50 | 6.39 | 6.39 | 6.39 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pIC50 | 6.19 | 6.19 | 6.19 | ChEMBL |
5-HT6 | 5HT6R | Human | 5-Hydroxytryptamine | A | pIC50 | 5.72 | 5.72 | 5.72 | ChEMBL |
5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pIC50 | 6.2 | 6.2 | 6.2 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pIC50 | 5.97 | 5.97 | 5.97 | ChEMBL |
5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pIC50 | 6.49 | 6.49 | 6.49 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pIC50 | 5.43 | 5.43 | 5.43 | ChEMBL |
5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pIC50 | 7.03 | 7.03 | 7.03 | ChEMBL |