CHEMBL189089


SMILES CCCCN(CC)c1cc(C)nc2c1NC(=O)CN2c1ccc(OC)cc1C
InChIKey LYSNALHFMZZUFA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 382.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CRF1 CRFR1 Human Corticotropin-releasing factor B1 pKi 8.4 8.4 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CRF1 CRFR1 Rat Corticotropin-releasing factor B1 pIC50 9.04 9.04 9.04 ChEMBL