bupranolol


SMILES OC(COc1cc(C)ccc1Cl)CNC(C)(C)C
InChIKey HQIRNZOQPUAHHV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 271.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKi 7.3 8.15 9.0 Guide to Pharmacology
β2 ADRB2 Human Adrenoceptors A pKi 8.3 9.1 9.9 Guide to Pharmacology
β3 ADRB3 Human Adrenoceptors A pKi 6.8 7.05 7.3 Guide to Pharmacology
β1 ADRB1 Human Adrenoceptors A pKi 8.05 8.05 8.05 Drug Central
β2 ADRB2 Human Adrenoceptors A pKi 8.04 8.04 8.04 Drug Central
β3 ADRB3 Human Adrenoceptors A pKi 8.14 8.14 8.14 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Rat Adrenoceptors A pA2 9.0 9.0 9.0 Guide to Pharmacology